martes, 22 de noviembre de 2011

GRAVIOLA: Anona muricata L.


Graviola is a small tree 8 to 10 m high, cultivated in almost all tropical America. It has a fruits from 15 to 20 cm long.

Actually its importance lies in the possibility of being used to relieve some discomfort because their leaves are substances such as acetogenins, which have an activity similar to that of products used in chemotherapy (eg adriamycin) with the quality of not presenting their side effects.

STUDIES
Complement Graviola, several studies indicate that consumption may be beneficial:

  • A study conducted at Purdue University in California, demonstrated that the acetogenins can selectively inhibit the growth of cancer cells and also inhibit the growth of tumor cells resistant to doxorubicin (chemotherapeutic drug), respecting the integrity of cells healthy tissue. In another study conducted by scientists at the University, it was demonstrated that the acetogenins of soursop (graviola) are extremely powerful to have an ED50 (lethal dose 50) of up to 10 to 9 micrograms per milliliter, resulting to have about 10,000 times the power of adriamycin.
  • Studies from 1998 to 2000 by McLaughlin and Chih HW, Chui HF have shown that acetogenins are inhibitors of complex I of oxidative ng fosforilaci chain thus block the formation of ATP energy needed by the cancer cell that puts in operating your pump P-glycoprotein-mediated, that lets you stay active. Acetogenins, also inhibit the ubiquinone oxidase, NADH-dependent enzyme is peculiar in the plasma membrane of the cancer cell. McLaughlin did his research and Bullatacinone Bullatacin acetogenins.

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